Move over, boring old side effects—GLP-1 weight loss drugs are shaking things up with a wild carnival of bodily rebellions. Forget just losing weight; users are reporting everything from “Ozempic feet,” where your toes apparently develop a mysterious vendetta against footwear, to cavities that pop up faster than your willpower at a donut sale. And if you thought a runny nose was reserved for sniffly seasons, think again—apparently these meds have declared war on your sinuses too.

These drugs, beloved for their appetite-zapping superpowers, also moonlight as mischievous tricksters: they slow your digestion to a crawl, turning your gut into a sluggish snail, while simultaneously inviting gallstone attacks and the dreaded bile duct drama. Some folks even end up with faces so hollowed out, they could audition for a zombie flick. Meanwhile, your heart races like it’s training for the Olympics—just to keep things thrilling.

Doctors are still scratching their heads, trying to keep patients on these magical mystery drugs despite a dizzying lineup of nausea, constipation, and abdominal pain worthy of a soap opera subplot. So if you’re thinking of jumping on the GLP-1 bandwagon, be prepared: your body might throw a weirdly spectacular tantrum before it gives you the skinny on true weight loss.